Lyophilization is the process of creating a stable preparation of a substance by rapid freezing and dehydration of the frozen product under high vacuum. PCRstable overcomes the manufacturing challenges of producing cartridges using lyophilized reagents. Unlike lyophilization, PCRstable reagents are prepared at ambient temperatures and stable in higher humidity. They are amenable to any chip, cartridge, or cassette platform, and don’t require difficult handling with tweezers like lyospheres.