Reagents & MDx Kits

Control & Stabilize Your Assays at Ambient Temperature

Assay developers face a number of challenges. Components (e.g. Taq polymerase) in chips and cartridges used in POC or molecular diagnostic platforms often require lyophilization techniques that need months of expensive development and production time. Additionally, the lyophilized components are susceptible to humidity during transport, storage and use which can reduce robustness. Besides lyophilization, PCR or RT-PCR assays may use low quantity/quality DNA or RNA templates and are difficult to amplify. Another common challenge are assays with inhibitors, such as heme from blood samples.

AssayStable and PCRstable are services that preserve and stabilize assays (PCR, qPCR, RT-qPCR, immunoassays, protein assays, controls) at ambient temperature.

ReadyDry PCR Stabilizer is a kit that preserves and stabilizes PCR assays at ambient temperatures after simple air drying.

PCRboost is a kit that improves sensitivity and specificity in PCR and RT-PCR reactions.

Reagents & MDx Kits- Advance Your Assay

ParameterAssayStable/PCRstableReadyDry PCRPCRboost
AssaysPCR, qPCR, RT-qPCR, Immunoassays, Protein Assays, ControlsDNA/PCRDNA & RNA
PCR/RT-PCR
Formats StabilizedLiquid and DryLiquid and DryLiquid
Key AdvantageCustomizedDIY stabilizationReplaces reaction water with PCRboost
Format
ServiceScreening Kit w/8 Stabilizers or vials
(5 X 1ml, 8 X 1ml)
Kit
150ul, 1ml, 10ml
Use CaseLab-on-a-Chip, POC
Reduce valves/solid supports/temporal separations
Extend shelf life, eliminate lyophilizationLow copy number or degraded template

The Biomatrica Advantage

Simplify Design: Removing valves, supports, and separations greatly simplifies design, cost, and manufacturability of chips and POC devices.

Stability: Extend shelf-life and prevent loss due to high-humidity.

Manufacturing: AssayStable and PCRstable are in-line processes that facilitate operations- requiring no outsourcing or in-house lyophilization. Additionally, there are no small lyophilized beads to handle, streamlining assembly.

No Cold Chain/Go Green: Simplify transit and storage by removing cold-chain. Eliminate freezers and dry ice shipments, while lowering utility and emergency power expenses.

Security: Protected against power-failures.

Rapid Development: All reagents included in screening kit to quickly optimize your PCR assay for ambient storage and shipment.

Stability: Extend shelf-life and prevent loss due to high-humidity.

Manufacturing: Easy air-dry technique keeps costs to a minimum. No lyophilizer or extra equipment needed.

No Cold Chain/Go Green: Simplify transit and storage by removing cold-chain. Eliminate freezers and dry ice shipments, while lowering utility and emergency power expenses.

Security: Protect your assays against power-failures.

Sensitivity: Generate data from low copy transcripts (e.g. early viral load) and rare templates (e.g. DNA from ancient bones).

Specificity: Improve performance from degraded samples including FFPE and blood.

Overcome PCR Inhibitors: Amplify samples containing heme, humic acid, and indigo dye.

Ease of Use: Replace only the water in the PCR reaction- no other changes needed.

Learn More

Hard Lessons Learned:

Impacts of Pre-Analytical Variance on Liquid Biopsy Clinical Trials

 This white-paper explores how upstream assay factors impacted six clinical trials. Encompassing both regional and global teams, learn the commonalities in six trials that initially fell short and the likely responsible mechanisms.

Download White-Paper

Get the Most from Your Assay

We Can Help You:

Improve Sensitivity
Reduce Pre-analytical Variations
Ease Shipping & Storage Logistics
Increase User Compliance
Improve Assay Throughput

Contact Us & Learn More

BIOMATRICA
5627 Oberlin Drive
Suite 120
San Diego, CA 92121
Tel: 858-550-0308
Fax: 858-678-0597
Email: orders@biomatrica.com